Erratum to: Cetuximab-induced skin exanthema: prophylactic and reactive skin therapy are equally effective
نویسندگان
چکیده
منابع مشابه
Cetuximab-induced skin exanthema: Improvement by a reactive skin therapy.
More than 80% of patients treated with cetuximab develop an acneiform follicular skin exanthema. Grade 3 exanthema develops in 9-19% of these cases, bearing the risk of cetuximab dose-reduction or cessation. We retrospectively analysed a cohort of 20 patients treated with cetuximab and an in-house reactive skin protocol upon development of an exanthema. The reactive skin protocol was built up a...
متن کاملManagement of cetuximab-induced skin toxicity with the prophylactic use of topical vitamin K1 cream
Cetuximab is an immunoglobulin G1 monoclonal antibody that binds to the extracellular domain of the epidermal growth factor receptor (EGFR) blocking ligand-induced auto-phosphorylation and subsequent receptor mediated signalling.1,2 Cetuximab in combination with chemotherapy is effective in the treatment of EGFR-expressing tumors including metastatic colorectal cancer (mCRC).2,3 EGFR is strongl...
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A highly significant, but unanswered, question in the pathogenesis of psoriasis relates to how normal appearing and diseased skin can coexist, undergo spontaneous flares and remissions, and yet appear to be genetically acquired. A plausible explanation for these disparate observations is that there is a basic defect in epidermal proliferation of skin of subjects with psoriasis and that disease ...
متن کاملComparison of Skin Erythema and Melanin Level in Sulfur Mustard Induced Chronic Skin Lesions and Normal Skin
Background: Sulfur mustard gas is a chemical agent that has been used in many wars, especially in Iran-Iraq war. This chemical agent affects many organs including lungs, eyes and skin, causing numerous acute and chronic lesions including erythema and hyperpigmentation, respectively. This study was conducted to evaluate erythema and melanin in subjects with a history of exposure to sulfur ...
متن کاملCetuximab in Refractory Skin Cancer Treatment
OBJECTIVES Non-melanoma skin cancer is the most common malignancy in US, with an annual incidence of in excess of 1.5 million cases. In the majority of cases, locoregional treatment is curative and systemic therapy is not indicated. Platinum-based chemotherapy regimens have been used most commonly in refractory cases. The use of cetuximab, a monoclonal antibody targeting epidermal growth factor...
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ژورنال
عنوان ژورنال: Journal of Cancer Research and Clinical Oncology
سال: 2013
ISSN: 0171-5216,1432-1335
DOI: 10.1007/s00432-013-1507-0